Climate change is one of the biggest challenges for developing countries, affecting almost all aspects of people’s lives. The resulting impacts cover the agricultural, health and natural resources sectors. In the context of these countries, the inability to adapt to climate change can exacerbate poverty and widen social inequalities. The agricultural sector is very vulnerable to extreme weather fluctuations. Countries such as Bangladesh and Indonesia, which depend on agricultural output, are seeing production decline due to rising temperatures and erratic rainfall patterns. Rice crops, one of the main commodities in this region, are threatened with crop failure. This not only has the potential to increase food prices, but also disrupts the food security of communities that are already vulnerable. Public health is also threatened by climate change. Increased temperature and humidity create an ideal environment for the spread of disease. Tropical countries, such as Myanmar and Kenya, record spikes in malaria and dengue fever cases during the prolonged rainy season. In addition, the quality of clean water is decreasing due to floods which bring contamination, thereby threatening the health of residents. Another natural resource affected is forests. Many developing countries rely on forests as a source of livelihood and natural habitat. Deforestation caused by increasing temperatures and unsustainable human activities makes ecosystems increasingly fragile. Countries like Brazil have taken steps to combat deforestation, but still face major challenges from industrial and agricultural development. The social and economic impacts of climate change in developing countries are very significant. Internal migration is one response to natural disasters that often occur due to climate change. Residents in remote areas are often forced to leave their homes to seek a better life in urban areas. This creates an additional burden on the city’s already congested infrastructure. Apart from that, social injustice is also increasing. Vulnerable groups, such as women and children, are often the main victims of the impacts of climate change. Many of them do not have adequate access to the resources or support needed to adapt. Taking these aspects into account, it is important for governments and international organizations to design policies that are inclusive and sustainable. Mitigation and adaptation efforts are the keys to facing this crisis. Investments in green technology and educational programs to raise awareness of climate change are essential. Apart from that, international cooperation is also needed to overcome this challenge comprehensively. Developing countries need to get financial and technical support from developed countries to build infrastructure and agricultural systems that are more resilient to climate change. It is important to understand that this problem is not just the responsibility of developing countries. The whole world must collaborate in efforts to reduce greenhouse gas emissions and encourage more sustainable practices. Small changes made at the local level can have a significant positive impact on global society. Building awareness of the importance of collective action to address climate change is urgently needed, especially to ensure sustainability for future generations.